pybigwig

80 / 100 · Low risk

Fine to try. Some of what it can do is expected: a coding skill usually runs build and test commands.

By stanfish06/skillquarium (GitHub) · coding · 12 stars · scanned at commit f748ea9

Fast Python I/O for BigWig (continuous genome signal) and BigBed (interval annotation) files via libBigWig. Use for random-access signal queries at specific genomic coordinates (bw.values, bw.stats), computing per-region summary statistics (mean/max/coverage) over a BED file of regions, writing custom BigWig tracks from numpy arrays, and loading ChIP-seq/ATAC-seq/RNA-seq/methylation coverage tracks (e.g. produced by deeptools bamCoverage) into pandas/numpy for downstream analysis or ML feature …

Works with any agent that supports SKILL.md skills.

What this skill can do

Downloads and installs other software

The author does not mention this.

Found in 3 places.

skills/pybigwig/SKILL.md, line 10compatibility: Requires Python 3.9+ and pyBigWig 0.3.x (current 0.3.25). This is a C extension over libBigWig — bioconda ships prebuilt packages for linux-64, l
skills/pybigwig/SKILL.md, line 25uv pip install pyBigWig
skills/pybigwig/SKILL.md, line 154- **Missing libcurl/zlib when building from source.** If a prebuilt wheel isn't available for your platform, `pip install pyBigWig` fails with a linker error un

Runs commands on your computer

The author does not mention this. Expected for a coding skill.

Found in 1 place.

skills/pybigwig/SKILL.md, line 25uv pip install pyBigWig

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'pybigwig' ] || [ -L ~/.agents/skills/'pybigwig' ]; then echo 'A skill folder named pybigwig already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/stanfish06/skillquarium' "$d" && git -C "$d" checkout --quiet 'f748ea91aa51ce8fc42c27c809dba73a8377b1d5' -- 'skills/pybigwig' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/pybigwig' ~/.agents/skills/'pybigwig' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'pybigwig' ~/.claude/skills/'pybigwig' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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Score history

Date	Version	Score
2026-11-08	`f748ea9`	80