boltzgen

80 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · design · 17 stars · scanned at commit 908229c

All-atom protein design using BoltzGen diffusion model. Use this skill when: (1) Need side-chain aware design from the start, (2) Designing around small molecules or ligands, (3) Want all-atom diffusion (not just backbone), (4) Require precise binding geometries, (5) Using YAML-based configuration. For backbone-only generation, use rfdiffusion. For sequence-only design, use proteinmpnn. For structure validation, use boltz.

Works with any agent that supports SKILL.md skills.

What this skill can do

Runs commands on your computer

The author does not mention this.

Found in 3 places.

skills/boltzgen/SKILL.md, line 40git clone https://github.com/hgbrian/biomodals && cd biomodals
skills/boltzgen/SKILL.md, line 61git clone https://github.com/HannesStark/boltzgen.git
skills/boltzgen/SKILL.md, line 264find output -name "*.cif" | wc -l # Should match num_samples

Downloads and installs other software

The author does not mention this.

Found in 2 places.

skills/boltzgen/SKILL.md, line 63pip install -e .
skills/boltzgen/SKILL.md, line 283| `modal: command not found` | Modal CLI not installed | Run `pip install modal && modal setup` |

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'boltzgen' ] || [ -L ~/.agents/skills/'boltzgen' ]; then echo 'A skill folder named boltzgen already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/boltzgen' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/boltzgen' ~/.agents/skills/'boltzgen' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'boltzgen' ~/.claude/skills/'boltzgen' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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Score history

Date	Version	Score
2026-11-11	`908229c`	80

Also found in

Identical copies of this skill exist at:

BioTender-max/awesome-bio-agent-skills/skills/adaptyv/boltzgen