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bio-systems-biology-gene-essentiality

85 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · marketing · 17 stars · scanned at commit 908229c

Performs in-silico single and double gene deletions, condition-dependent essentiality, and synthetic-lethality screens on genome-scale metabolic models with COBRApy, evaluating gene-protein-reaction rules and comparing FBA re-optimization against MOMA/ROOM minimal-adjustment. Use when predicting essential genes, finding synthetic-lethal pairs for drug targets, choosing a growth cutoff, deciding FBA vs MOMA vs ROOM for a knockout, making essentiality medium-specific to match an experiment, or va…

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-systems-biology-gene-essentiality' ] || [ -L ~/.agents/skills/'bio-systems-biology-gene-essentiality' ]; then echo 'A skill folder named bio-systems-biology-gene-essentiality already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-systems-biology-gene-essentiality' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-systems-biology-gene-essentiality' ~/.agents/skills/'bio-systems-biology-gene-essentiality' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-systems-biology-gene-essentiality' ~/.claude/skills/'bio-systems-biology-gene-essentiality' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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