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bio-structural-biology-binding-site-detection

80 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · other · 17 stars · scanned at commit 908229c

Detects putative ligand-binding pockets and druggable cavities de novo on an apo protein structure with fpocket, P2Rank, CASTp, and DoGSiteScorer, ranking them by druggability/ligandability score. Use when detecting cavities on an apo structure with no bound ligand; choosing geometric pocket enumeration (fpocket alpha-spheres, CASTp) vs ML ligandability scoring (P2Rank, DoGSiteScorer); recognizing that a geometric cavity is a hypothesis, not automatically a functional or druggable site (may be …

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-structural-biology-binding-site-detection' ] || [ -L ~/.agents/skills/'bio-structural-biology-binding-site-detection' ]; then echo 'A skill folder named bio-structural-biology-binding-site-detection already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-structural-biology-binding-site-detection' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-structural-biology-binding-site-detection' ~/.agents/skills/'bio-structural-biology-binding-site-detection' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-structural-biology-binding-site-detection' ~/.claude/skills/'bio-structural-biology-binding-site-detection' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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