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bio-single-cell-differential-abundance

85 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · coding · 17 stars · scanned at commit 908229c

Test whether cell-type proportions or composition changed between conditions in single-cell data using Milo (miloR), scCODA, sccomp, and propeller. Use when comparing cell-type proportions / composition between conditions, asking which populations expanded or contracted with treatment or disease, running neighborhood-level (cluster-free) abundance testing, or guarding against compositional shifts that masquerade as differential expression.

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-single-cell-differential-abundance' ] || [ -L ~/.agents/skills/'bio-single-cell-differential-abundance' ]; then echo 'A skill folder named bio-single-cell-differential-abundance already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-single-cell-differential-abundance' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-single-cell-differential-abundance' ~/.agents/skills/'bio-single-cell-differential-abundance' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-single-cell-differential-abundance' ~/.claude/skills/'bio-single-cell-differential-abundance' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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