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bio-rna-structure-structure-probing

80 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · data · 17 stars · scanned at commit 908229c

Processes experimental RNA structure probing data (SHAPE-MaP, DMS-MaPseq) into per-nucleotide reactivity profiles with ShapeMapper2, then uses them as soft restraints on thermodynamic folding. Covers reagent and readout choice (SHAPE vs DMS, mutational-profiling vs RT-stop), the three control samples, per-transcript normalization, the Deigan vs Zarringhalam pseudo-energy models, in-cell versus in-vitro interpretation, and multi-conformation deconvolution. Use when converting probing reads to re…

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-rna-structure-structure-probing' ] || [ -L ~/.agents/skills/'bio-rna-structure-structure-probing' ]; then echo 'A skill folder named bio-rna-structure-structure-probing already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-rna-structure-structure-probing' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-rna-structure-structure-probing' ~/.agents/skills/'bio-rna-structure-structure-probing' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-rna-structure-structure-probing' ~/.claude/skills/'bio-rna-structure-structure-probing' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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