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bio-methylation-ewas-design

85 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · design · 17 stars · scanned at commit 908229c

Designs and defends an epigenome-wide association study (EWAS) on 450K/EPIC array or bisulfite methylation - the layer deciding whether a hit is credible. Covers the confounding hierarchy (cell composition covariates as the dominant confounder, batch/Sentrix chip/array position, age/sex, smoking AHRR cg05575921, ancestry/mQTL, reverse causation), chip randomization (no-rescue theorem), surrogate variable analysis sva/SmartSVA, ComBat, RUVm, over-correction, genomic inflation lambda vs GWAS geno…

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-methylation-ewas-design' ] || [ -L ~/.agents/skills/'bio-methylation-ewas-design' ]; then echo 'A skill folder named bio-methylation-ewas-design already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-methylation-ewas-design' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-methylation-ewas-design' ~/.agents/skills/'bio-methylation-ewas-design' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-methylation-ewas-design' ~/.claude/skills/'bio-methylation-ewas-design' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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