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bio-methylation-cell-type-deconvolution

100 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · design · 17 stars · scanned at commit 908229c

Estimates cell-type composition from bulk DNA methylation and uses it to defuse the single biggest EWAS confounder. Covers reference-based deconvolution (Houseman constrained-projection, minfi estimateCellCounts2 with FlowSorted.Blood.EPIC + IDOL-optimized libraries, EpiDISH RPC/CBS/CP, 12-cell extended, cord-blood nRBC references, EpiSCORE/hepidish for solid tissue), reference-free correction (ReFACTor, RefFreeEWAS, SVA), using fractions as covariates vs the compositionality/collinearity trap,…

Works with any agent that supports SKILL.md skills.

What this skill can do

We found nothing in the files we read that matches our rules. That does not prove the skill is safe: see the limits of static scanning.

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-methylation-cell-type-deconvolution' ] || [ -L ~/.agents/skills/'bio-methylation-cell-type-deconvolution' ]; then echo 'A skill folder named bio-methylation-cell-type-deconvolution already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-methylation-cell-type-deconvolution' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-methylation-cell-type-deconvolution' ~/.agents/skills/'bio-methylation-cell-type-deconvolution' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-methylation-cell-type-deconvolution' ~/.claude/skills/'bio-methylation-cell-type-deconvolution' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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