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bio-methylation-calling

95 / 100 · Low risk

Fine to try. Some of what it can do is expected: a coding skill usually runs build and test commands.

By lilinji/GeneTind-Life-Skills (GitHub) · coding · 17 stars · scanned at commit 908229c

Extracts per-cytosine methylation calls from aligned bisulfite/EM-seq reads with bismark_methylation_extractor (Bismark BAM) or the aligner-agnostic MethylDackel/BISCUIT (bwa-meth BAM), producing the beta value M/(M+U) as a coverage file, bedGraph, or genome-wide cytosine report across CpG/CHG/CHH context. Covers conversion-rate QC as the first gate, the 5mC vs 5hmC summed caveat, variant-aware calling so a C/T SNP does not masquerade as unmethylation, paired-end --no_overlap double-counting, s…

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-methylation-calling' ] || [ -L ~/.agents/skills/'bio-methylation-calling' ]; then echo 'A skill folder named bio-methylation-calling already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-methylation-calling' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-methylation-calling' ~/.agents/skills/'bio-methylation-calling' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-methylation-calling' ~/.claude/skills/'bio-methylation-calling' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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