← All skills

bio-hi-c-analysis-tad-detection

80 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · data · 17 stars · scanned at commit 908229c

Detects TAD boundaries from balanced Hi-C contact matrices via the diamond-window insulation score (cooltools insulation) and HiCExplorer hicFindTADs, returning a continuous log2 insulation track, valley-prominence boundary_strength, and Li/Otsu-thresholded is_boundary flags across a list of window sizes. Covers the multi-scale window sweep (sub-TAD to compartment-domain), why the boundary is reproducible but the domain partition is not, cross-condition comparison via differential SCORE not dif…

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-hi-c-analysis-tad-detection' ] || [ -L ~/.agents/skills/'bio-hi-c-analysis-tad-detection' ]; then echo 'A skill folder named bio-hi-c-analysis-tad-detection already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-hi-c-analysis-tad-detection' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-hi-c-analysis-tad-detection' ~/.agents/skills/'bio-hi-c-analysis-tad-detection' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-hi-c-analysis-tad-detection' ~/.claude/skills/'bio-hi-c-analysis-tad-detection' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

Badge for your README

The badge for lilinji/GeneTind-Life-Skills shows the score of its lowest-scoring skill.

[![SkillTrust](https://zalavijaysinh.github.io/skilltrust/badges/lilinji/GeneTind-Life-Skills.svg)](https://zalavijaysinh.github.io/skilltrust/repos/lilinji/GeneTind-Life-Skills/)

Score history