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bio-hi-c-analysis-matrix-operations

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Check before installing.

By lilinji/GeneTind-Life-Skills (GitHub) · other · 17 stars · scanned at commit 908229c

Balances Hi-C contact matrices (ICE via cooler.balance_cooler, KR/SCALE/VC context), computes distance-decay expected with cooltools (expected_cis per-diagonal P(s), expected_trans scalar), builds observed/expected (O/E) matrices, and diagnoses polymer state from the P(s) log-derivative. Covers the within-matrix-vs-cross-sample distinction (balancing is NOT a normalizer), the equal-visibility assumption that CNV/aneuploidy violates (use raw counts for copy-number), cis-only balancing, mad_max/b…

Works with any agent that supports SKILL.md skills.

What this skill can do

Safer alternatives

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Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-hi-c-analysis-matrix-operations' ] || [ -L ~/.agents/skills/'bio-hi-c-analysis-matrix-operations' ]; then echo 'A skill folder named bio-hi-c-analysis-matrix-operations already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-hi-c-analysis-matrix-operations' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-hi-c-analysis-matrix-operations' ~/.agents/skills/'bio-hi-c-analysis-matrix-operations' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-hi-c-analysis-matrix-operations' ~/.claude/skills/'bio-hi-c-analysis-matrix-operations' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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