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bio-gene-regulatory-networks-perturbation-simulation

85 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · productivity · 17 stars · scanned at commit 908229c

Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation …

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-gene-regulatory-networks-perturbation-simulation' ] || [ -L ~/.agents/skills/'bio-gene-regulatory-networks-perturbation-simulation' ]; then echo 'A skill folder named bio-gene-regulatory-networks-perturbation-simulation already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-gene-regulatory-networks-perturbation-simulation' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-gene-regulatory-networks-perturbation-simulation' ~/.agents/skills/'bio-gene-regulatory-networks-perturbation-simulation' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-gene-regulatory-networks-perturbation-simulation' ~/.claude/skills/'bio-gene-regulatory-networks-perturbation-simulation' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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