← All skills

bio-causal-genomics-proteome-mr-drug-target

95 / 100 · Low risk

Fine to try.

By lilinji/GeneTind-Life-Skills (GitHub) · other · 17 stars · scanned at commit 908229c

Runs cis-pQTL Mendelian randomization for drug-target validation using UKB-PPP (Olink), deCODE (SomaScan), Fenland, INTERVAL, ARIC, and FinnGen-PPP proteomes plus colocalization triangulation, phenome-wide on-target adverse-effect scans, cross-platform Olink/SomaScan replication, and PAV (protein-altering variant) sensitivity. Use when nominating or de-risking a drug target from plasma-proteome GWAS, mimicking pharmacological inhibition via cis-pQTL instruments, separating shared-causal from LD…

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'bio-causal-genomics-proteome-mr-drug-target' ] || [ -L ~/.agents/skills/'bio-causal-genomics-proteome-mr-drug-target' ]; then echo 'A skill folder named bio-causal-genomics-proteome-mr-drug-target already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/lilinji/GeneTind-Life-Skills' "$d" && git -C "$d" checkout --quiet '908229c955510a1841b216e8bf58f6b22818d4dc' -- 'skills/bio-causal-genomics-proteome-mr-drug-target' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/bio-causal-genomics-proteome-mr-drug-target' ~/.agents/skills/'bio-causal-genomics-proteome-mr-drug-target' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'bio-causal-genomics-proteome-mr-drug-target' ~/.claude/skills/'bio-causal-genomics-proteome-mr-drug-target' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

Badge for your README

The badge for lilinji/GeneTind-Life-Skills shows the score of its lowest-scoring skill.

[![SkillTrust](https://zalavijaysinh.github.io/skilltrust/badges/lilinji/GeneTind-Life-Skills.svg)](https://zalavijaysinh.github.io/skilltrust/repos/lilinji/GeneTind-Life-Skills/)

Score history