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encode-database
77 / 100 · Review before installing
Check before installing. Some of what it can do is expected: a coding skill usually runs build and test commands.
By jaechang-hits/SciAgent-Skills (GitHub) · coding · 388 stars · scanned at commit 65d6ceb
ENCODE Portal REST API for regulatory genomics: TF ChIP-seq, ATAC-seq/DNase-seq peaks, histone marks, and RNA-seq across 1000+ cell types. Search experiments by assay/biosample/target; download BED/bigWig; retrieve SCREEN cCREs by region or gene. Use to annotate variants with regulatory tracks, find open chromatin in a cell type, or fetch peak files for ChIP/ATAC analysis. For regulatory variant scoring use regulomedb-database; for GWAS associations use gwas-database.
Works with any agent that supports SKILL.md skills.
What this skill can do
Downloads and installs other software
The author does not mention this.
Found in 1 place.
Runs commands on your computer
The author does not mention this. Expected for a coding skill.
Found in 1 place.
Connects to the internet
This is disclosed by the author in the skill's SKILL.md or README.
Found in 17 places.
Show 14 more
- skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 180
import urllib.request - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 185
urllib.request.urlretrieve(download_url, output_path) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 219
r = requests.post(f"{SCREEN_BASE}/search/", json=payload, timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 265
r = requests.get( - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 319
r = requests.get(f"{BASE}/search/", params=params, timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 365
r = requests.get(f"{BASE}/search/", params=params, timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 401
r = requests.get(f"{BASE}/experiments/{accession}/?format=json", timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 501
r = requests.get(f"{BASE}/search/", params=params, timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 516
r2 = requests.get(peak["download_url"], timeout=120, stream=True) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 554
r = requests.post(f"{SCREEN_BASE}/search/", json=payload, timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 634
r = requests.get(f"{BASE}/search/", params=params, timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 705
r = requests.get( - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 729
r = requests.get(f"{BASE}/experiments/{accession}/?format=json", timeout=30) - skills/genomics-bioinformatics/databases/encode-database/SKILL.md, line 765
r = requests.get(f"{BASE}/search/", params=params, timeout=30)
Safer alternatives
Low-risk skills in the same category (coding) that look related. Check that one does what you need.
Install
Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.
if [ -e ~/.agents/skills/'encode-database' ] || [ -L ~/.agents/skills/'encode-database' ]; then echo 'A skill folder named encode-database already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/jaechang-hits/SciAgent-Skills' "$d" && git -C "$d" checkout --quiet '65d6ceb875e20b751ffb3a6d8ee19516558789e1' -- 'skills/genomics-bioinformatics/databases/encode-database' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/genomics-bioinformatics/databases/encode-database' ~/.agents/skills/'encode-database' && rm -rf "$d"; fi
Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'encode-database' ~/.claude/skills/'encode-database' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.
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The badge for jaechang-hits/SciAgent-Skills shows the score of its lowest-scoring skill.

[](https://zalavijaysinh.github.io/skilltrust/repos/jaechang-hits/SciAgent-Skills/)
Score history
| Date | Version | Score |
|---|
| 2026-11-07 | 65d6ceb | 100 |