← All skills

clinical-variant-prioritizer

95 / 100 · Low risk

Fine to try.

By ClawBio/ClawBio (GitHub) · other · 1,182 stars · scanned at commit a4a8c72

Screen a genotype set (array or WGS-derived) against OMIM-morbid, ACMG-SF and Hereditary-Cancer gene panels and prioritise carried variants by ClinVar significance, gnomAD frequency, inheritance model and zygosity, following the pathogenicity-screening method of Corpas et al. 2021 (Whole Genome Interpretation for a Family of Five).

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'clinical-variant-prioritizer' ] || [ -L ~/.agents/skills/'clinical-variant-prioritizer' ]; then echo 'A skill folder named clinical-variant-prioritizer already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/ClawBio/ClawBio' "$d" && git -C "$d" checkout --quiet 'a4a8c7281c8ddd8a0b84c5cffae5d9a0760f40fe' -- 'skills/clinical-variant-prioritizer' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/clinical-variant-prioritizer' ~/.agents/skills/'clinical-variant-prioritizer' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'clinical-variant-prioritizer' ~/.claude/skills/'clinical-variant-prioritizer' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

Badge for your README

The badge for ClawBio/ClawBio shows the score of its lowest-scoring skill.

[![SkillTrust](https://zalavijaysinh.github.io/skilltrust/badges/ClawBio/ClawBio.svg)](https://zalavijaysinh.github.io/skilltrust/repos/ClawBio/ClawBio/)

Score history