pkpd-modeling

82 / 100 · Low risk

Fine to try.

By boisenoise/skills-collections (GitHub) · data · 12 stars · scanned at commit 419c39f

Pharmacokinetic and pharmacodynamic modelling and simulation - non-compartmental analysis, compartmental and population PK, PK/PD and exposure-response, TMDD, PBPK orientation, bioequivalence, allometric scaling and first-in-human dose, drug interaction prediction, and Bayesian therapeutic drug monitoring. Use when analysing concentration-time data, deriving exposure metrics, fitting PK or PD models, or evaluating dosing regimens. Triggers include "pharmacokinetics", "pharmacodynamics", "PK/PD"…

Works with any agent that supports SKILL.md skills.

What this skill can do

Runs commands on your computer

This is disclosed by the author in the skill's SKILL.md or README.

Found in 10 places.

skills/kdense-pkpd-modeling/SKILL.md, line 43cd skills/pkpd-modeling/scripts
skills/kdense-pkpd-modeling/SKILL.md, line 60python3 nca.py -i profile.csv --dose 100 --route extravascular --partial-auc 0-24
skills/kdense-pkpd-modeling/SKILL.md, line 92python3 fit_compartmental.py -i profile.csv --dose 500 --route iv-bolus --compare 1cmt,2cmt,3cmt

Show 7 more

skills/kdense-pkpd-modeling/SKILL.md, line 115python3 check_popk_dataset.py -i nmdata.csv --covariates WT,CRCL --time-varying WT
skills/kdense-pkpd-modeling/SKILL.md, line 136python3 simulate_regimen.py --cl 5 --v 40 --dose 500 --interval 12 --n-doses 10 --steady-state
skills/kdense-pkpd-modeling/SKILL.md, line 154python3 exposure_response.py --emax -i er.csv --sigmoid
skills/kdense-pkpd-modeling/SKILL.md, line 173python3 bioequivalence.py -i be.csv --design 2x2 --metric AUC
skills/kdense-pkpd-modeling/SKILL.md, line 194python3 allometry_and_fih.py --scale --cl 5 --volume 40 --weight-from 70 --weight-to 6 --pma-weeks 44
skills/kdense-pkpd-modeling/SKILL.md, line 212python3 ddi_static.py --basic --ki 0.5 --imax 2 --fu 0.05 --dose 0.4
skills/kdense-pkpd-modeling/SKILL.md, line 235python3 tdm_bayes.py --model vancomycin-adult --weight 80 --crcl 75 --dose 1500 --interval 12 --doses-given 20 --level 18.2@11.5 --level 42@2 --target-auc24 500

Downloads and installs other software

The author does not mention this.

Found in 4 places.

skills/kdense-pkpd-modeling/scripts/bioequivalence.py, line 37raise SystemExit("bioequivalence.py needs scipy: uv pip install scipy") from exc
skills/kdense-pkpd-modeling/scripts/exposure_response.py, line 44raise SystemExit("exposure_response.py needs scipy: uv pip install scipy") from exc
skills/kdense-pkpd-modeling/scripts/fit_compartmental.py, line 49raise SystemExit("fit_compartmental.py needs scipy: uv pip install scipy") from exc

Show 1 more

skills/kdense-pkpd-modeling/scripts/tdm_bayes.py, line 27raise SystemExit("tdm_bayes.py needs scipy: uv pip install scipy") from exc

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'pkpd-modeling' ] || [ -L ~/.agents/skills/'pkpd-modeling' ]; then echo 'A skill folder named pkpd-modeling already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/boisenoise/skills-collections' "$d" && git -C "$d" checkout --quiet '419c39fde874b8baecbb36a397b967e0190a2ece' -- 'skills/kdense-pkpd-modeling' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/kdense-pkpd-modeling' ~/.agents/skills/'pkpd-modeling' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'pkpd-modeling' ~/.claude/skills/'pkpd-modeling' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

Badge for your README

The badge for boisenoise/skills-collections shows the score of its lowest-scoring skill.

SkillTrust badge for boisenoise/skills-collections

[![SkillTrust](https://zalavijaysinh.github.io/skilltrust/badges/boisenoise/skills-collections.svg)](https://zalavijaysinh.github.io/skilltrust/repos/boisenoise/skills-collections/)

Score history

Date	Version	Score
2026-11-12	`419c39f`	82
2026-11-08	`5fe45e5`	82
2026-11-06	`b89b2f5`	82

Also found in

Identical copies of this skill exist at:

LeoYeAI/agent-master-skills/skills/pkpd-modeling