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gtopdb-database
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By BioTender-max/awesome-bio-agent-skills (GitHub) · design · 219 stars · scanned at commit 8cbdd18
Query IUPHAR/BPS Guide to Pharmacology (GtoPdb) for receptor-ligand interactions, target/ligand metadata, families, and approved drugs. Affinities (pKi/pIC50/pKd), action (Agonist/Antagonist/etc.), species, structures (SMILES/InChI). No auth. Always resolve targets via geneSymbol/accession; most metadata lives in sub-resources (/databaseLinks, /structure, /synonyms).
Works with any agent that supports SKILL.md skills.
What this skill can do
Downloads and installs other software
The author does not mention this.
Found in 1 place.
Runs commands on your computer
The author does not mention this.
Found in 1 place.
Connects to the internet
This is disclosed by the author in the skill's SKILL.md or README.
Found in 21 places.
Show 17 more
- skills/sciagent/gtopdb-database/SKILL.md, line 99
r = requests.get(f"{BASE}/targets/{target_id}/databaseLinks", timeout=30) - skills/sciagent/gtopdb-database/SKILL.md, line 104
r = requests.get(f"{BASE}/targets/{target_id}/synonyms", timeout=30) - skills/sciagent/gtopdb-database/SKILL.md, line 129
r = requests.get(f"{BASE}/targets/{target_id}/interactions", timeout=60) - skills/sciagent/gtopdb-database/SKILL.md, line 166
r = requests.get(f"{BASE}/ligands/{ligand_id}", timeout=30) - skills/sciagent/gtopdb-database/SKILL.md, line 172
r = requests.get(f"{BASE}/ligands/{ligand_id}/structure", timeout=30) - skills/sciagent/gtopdb-database/SKILL.md, line 189
r = requests.get(f"{BASE}/ligands/{ligand_id}/databaseLinks", timeout=30) - skills/sciagent/gtopdb-database/SKILL.md, line 207
r = requests.get(f"{BASE}/targets/families", timeout=30) - skills/sciagent/gtopdb-database/SKILL.md, line 227
r = requests.get(f"{BASE}/ligands", params={"type": "Approved"}, timeout=60) - skills/sciagent/gtopdb-database/SKILL.md, line 278
t = requests.get(f"{BASE}/targets", - skills/sciagent/gtopdb-database/SKILL.md, line 283
ints = requests.get(f"{BASE}/targets/{tid}/interactions", timeout=60).json() - skills/sciagent/gtopdb-database/SKILL.md, line 296
lig = requests.get(f"{BASE}/ligands/{i['ligandId']}", timeout=30).json() - skills/sciagent/gtopdb-database/SKILL.md, line 322
r = requests.get(f"{BASE}/ligands/{ligand_id}/interactions", timeout=60) - skills/sciagent/gtopdb-database/SKILL.md, line 372
t = requests.get(f"{BASE}/targets", params={"geneSymbol": symbol}, timeout=30).json() - skills/sciagent/gtopdb-database/SKILL.md, line 375
links = requests.get(f"{BASE}/targets/{t[0]['targetId']}/databaseLinks", timeout=30).json() - skills/sciagent/gtopdb-database/SKILL.md, line 392
fams = requests.get(f"{BASE}/targets/families", timeout=30).json() - skills/sciagent/gtopdb-database/SKILL.md, line 398
ints = requests.get(f"{BASE}/targets/{tid}/interactions", timeout=60).json() - skills/sciagent/gtopdb-database/SKILL.md, line 400
lig = requests.get(f"{BASE}/ligands/{i['ligandId']}", timeout=30).json()
and 1 more places
Safer alternatives
Low-risk skills in the same category (design) that look related. Check that one does what you need.
Install
Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.
if [ -e ~/.agents/skills/'gtopdb-database' ] || [ -L ~/.agents/skills/'gtopdb-database' ]; then echo 'A skill folder named gtopdb-database already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/BioTender-max/awesome-bio-agent-skills' "$d" && git -C "$d" checkout --quiet '8cbdd18837aa6296c4e77616a03b323bd69b57b1' -- 'skills/sciagent/gtopdb-database' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/sciagent/gtopdb-database' ~/.agents/skills/'gtopdb-database' && rm -rf "$d"; fi
Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'gtopdb-database' ~/.claude/skills/'gtopdb-database' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.
Badge for your README
The badge for BioTender-max/awesome-bio-agent-skills shows the score of its lowest-scoring skill.

[](https://zalavijaysinh.github.io/skilltrust/repos/BioTender-max/awesome-bio-agent-skills/)
Score history
| Date | Version | Score |
|---|
| 2026-11-07 | 8cbdd18 | 77 |