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boltz

95 / 100 · Low risk

Fine to try.

By aipoch/open-science (GitHub) · research · 5,526 stars · scanned at commit c4ae79b

Structure prediction for protein, nucleic-acid, and small-molecule complexes with Boltz-2 (Passaro & Wohlwend et al. 2025, github.com/jwohlwend/boltz). Reach for this skill to validate designed binders against a target, to co-fold a protein with a SMILES or CCD ligand, or to get an open-source AlphaFold3 alternative with optional binding-affinity prediction.

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'boltz' ] || [ -L ~/.agents/skills/'boltz' ]; then echo 'A skill folder named boltz already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/aipoch/open-science' "$d" && git -C "$d" checkout --quiet 'c4ae79ba6ca5c97dcb1fb27518acda85319d7115' -- 'resources/skills/boltz' && mkdir -p ~/.agents/skills && cp -R "$d"/'resources/skills/boltz' ~/.agents/skills/'boltz' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'boltz' ~/.claude/skills/'boltz' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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Score history