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rfdiffusion

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Check before installing.

By adaptyvbio/protein-design-skills (GitHub) · design · 173 stars · scanned at commit 59dd633

Generate protein backbones using RFdiffusion, a diffusion-based generative model for de novo protein structure generation. Use this skill when: (1) Designing binder scaffolds for a target protein, (2) Generating novel protein backbones from scratch, (3) Scaffolding functional motifs into new proteins, (4) Specifying hotspot residues for interface design, (5) Creating symmetric oligomers. For sequence design after backbone generation, use proteinmpnn. For structure validation, use alphafold or c…

Works with any agent that supports SKILL.md skills.

What this skill can do

Safer alternatives

Low-risk skills in the same category (design) that look related. Check that one does what you need.

• 90 Low riskrfdiffusion-nimstanfish06/skillquarium · 12 stars

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'rfdiffusion' ] || [ -L ~/.agents/skills/'rfdiffusion' ]; then echo 'A skill folder named rfdiffusion already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/adaptyvbio/protein-design-skills' "$d" && git -C "$d" checkout --quiet '59dd63374314baa2fb1f9864f190775bd7466647' -- 'skills/rfdiffusion' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/rfdiffusion' ~/.agents/skills/'rfdiffusion' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'rfdiffusion' ~/.claude/skills/'rfdiffusion' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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