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foldseek

90 / 100 · Low risk

Fine to try.

By adaptyvbio/protein-design-skills (GitHub) · design · 173 stars · scanned at commit 59dd633

Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'foldseek' ] || [ -L ~/.agents/skills/'foldseek' ]; then echo 'A skill folder named foldseek already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/adaptyvbio/protein-design-skills' "$d" && git -C "$d" checkout --quiet '59dd63374314baa2fb1f9864f190775bd7466647' -- 'skills/foldseek' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/foldseek' ~/.agents/skills/'foldseek' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'foldseek' ~/.claude/skills/'foldseek' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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