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esm

80 / 100 · Low risk

Fine to try.

By adaptyvbio/protein-design-skills (GitHub) · design · 173 stars · scanned at commit 59dd633

ESM protein language models for embeddings, sequence scoring, structure prediction, and binder design. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) or mutation-effect scores, (2) Getting protein embeddings for clustering or filtering, (3) Predicting complex structures with ESMFold2, (4) Designing binders by inverting ESMFold2, (5) Filtering designs by sequence plausibility. For diffusion-based structure prediction, use boltz or chai. For QC thresholds, use protein-qc. For grad…

Works with any agent that supports SKILL.md skills.

What this skill can do

Install

Paste this into your terminal. It downloads exactly the version we scanned, not whatever is newest.

if [ -e ~/.agents/skills/'esm' ] || [ -L ~/.agents/skills/'esm' ]; then echo 'A skill folder named esm already exists — not replacing it' >&2; false; else d=$(mktemp -d) && git clone --quiet --filter=blob:none --no-checkout 'https://github.com/adaptyvbio/protein-design-skills' "$d" && git -C "$d" checkout --quiet '59dd63374314baa2fb1f9864f190775bd7466647' -- 'skills/esm' && mkdir -p ~/.agents/skills && cp -R "$d"/'skills/esm' ~/.agents/skills/'esm' && rm -rf "$d"; fi

Codex reads ~/.agents/skills directly. For Claude Code, Cursor, Copilot, Gemini CLI, Antigravity or OpenCode, also link it. For Claude Code: ln -s ~/.agents/skills/'esm' ~/.claude/skills/'esm' (other agents: ~/.cursor/skills, ~/.copilot/skills, ~/.gemini/skills, ~/.gemini/config/skills, ~/.config/opencode/skills). Or install through the finder skill, which does both.

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